China API [Name] Generic Name: Palonosetron Hydrochloride injection The quality and efficacy consistency of generic drugs were evaluated. The second generation 5-HT3 receptor antagonist, super antagonistic, long - lasting antiemetic. The only 5-HT3 receptor antagonist FDA-approved for the prevention of delayed chemotherapy-induced nausea and vomiting. [Indication] 1. To prevent nausea and vomiting which are induced by tumor treatment (Radiotherapy or chemotherapy) 2. To prevent nausea and vomiting after anesthesia and surgery. 3. To prevent postoperative nausea and vomiting within 24 hours after surgery. Development History On December 31, 1993, Hangzhou Jiuyuan Gene Engineering Co., Ltd. was registered and established in Hangzhou New High-tech Development Zone. On October 14, 1996,the company obtained the Trial-production Approval Number and New Drug Certificate of JILIFEN, the first rhG-CSF injection in China, making China become the third country able to manufacture the drug in large volumes following in the U.S and Japan. In June, 1998, the drug low molecular weight heparin sodium injection (JIPAILIN) was approved for production and marketing by Ministry of Health. On September 18, 2003,the company achieved a New Drug Certificate and Manufacture Approval of JIJUFEN, a platelet promoting drug (Recombinant Human Interleukin 11). In July, 2006, the company initiated the production and sales of the 4th product YINUOJIA (Enoxaparin Sodium Injection), indicating the first officially approved enoxaparin was born in China. The company was awarded as one of the first "National High-Tech Enterprises" in 2008. On December 19, the 5th product JIOUTING (Palonosetron Hydrochloride API and injection) officially got approval for manufacture. In 2010, the new product recombinant human bone repair material BMP-2 (GUYOUDAO) was manufactured and launched on market. In October, 2013,the company reformed marketing system and established a development strategy of "Marketing First, Total Marketing". In 2018, the company has initiated a major transformation, focusing on both innovative and generic drugs. In 2020, R&D center moved to Hangzhou Medicine valley. The company's sales exceeded 1 billion yuan. Company Honor National New High-tech Enterprise Key New High-tech Enterprise of National Torch Plan National superior enterprise of intellectual property Provincial New High-tech Research & Development Center Zhejiang Provincial Enterprise Technology Center Zhejiang Famous Trademark Zhejiang Jiuyuan Gene Engineering Biopharmaceutical Research InstituteChina API website:http://www.jiuyuan-gene.com/ap/
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