6. Critical Strike and Curses
Certain curses directly boost crit efficiency:

Assassin’s Mark: Increases chance to Path of exile currency crit, adds crit multiplier, and grants a chance to gain a power charge on kill. It’s the go-to curse for crit-based builds.

Sniper’s Mark (for projectile skills): Enhances projectile behavior and damage, but can be paired with crit-focused projectiles for synergy.

Interaction Tip: Linking curses to Blasphemy Support or triggering them with Curse on Hit ensures your crit buffs are always applied in combat.

7. Conditional Crit Multipliers
Certain sources of crit multiplier only apply in specific scenarios:

Against cursed enemies (e.g., Assassin’s Mark).

While holding a shield, dual-wielding, or using two-handed weapons (via passive tree or cluster jewels).

Against bleeding, poisoned, or shocked enemies, boosting specific builds like poison crit or elemental crit archetypes.

Interaction Tip: Plan your gear and passive choices around these conditional multipliers to POE currency for sale ensure uptime. For example, if your build constantly poisons, leverage "increased crit multi against poisoned enemies."